Glucocorticoids Suppress the Browning of Adipose Tissue via miR-19b in Male Mice
نویسندگان
چکیده
منابع مشابه
Glucocorticoids Transcriptionally Regulate miR-27b Expression Promoting Body Fat Accumulation Via Suppressing the Browning of White Adipose Tissue
Long-term glucocorticoid (GC) treatment induces central fat accumulation and metabolic dysfunction. We demonstrate that microRNA-27b (miR-27b) plays a central role in the pathogenesis of GC-induced central fat accumulation. Overexpression of miR-27b had the same effects as dexamethasone (DEX) treatment on the inhibition of brown adipose differentiation and the energy expenditure of primary adip...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 2017
ISSN: 1945-7170
DOI: 10.1210/en.2017-00566